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Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B

Glomerular podocytes are critical for the barrier function of the glomerulus in the kidney and their dysfunction causes protein leakage into the urine (proteinuria). Nephrin is a key podocyte protein, which regulates the actin cytoskeleton via tyrosine phosphorylation of its cytoplasmic domain. Here...

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Detalles Bibliográficos
Autores principales: Aoudjit, Lamine, Jiang, Ruihua, Lee, Tae Hoon, New, Laura A., Jones, Nina, Takano, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195428/
https://www.ncbi.nlm.nih.gov/pubmed/22013520
http://dx.doi.org/10.1155/2011/376543