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Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome

Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epide...

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Autores principales: Di Chiara, Tiziana, Argano, Christiano, Corrao, Salvatore, Scaglione, Rosario, Licata, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195429/
https://www.ncbi.nlm.nih.gov/pubmed/22013516
http://dx.doi.org/10.1155/2012/175245
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author Di Chiara, Tiziana
Argano, Christiano
Corrao, Salvatore
Scaglione, Rosario
Licata, Giuseppe
author_facet Di Chiara, Tiziana
Argano, Christiano
Corrao, Salvatore
Scaglione, Rosario
Licata, Giuseppe
author_sort Di Chiara, Tiziana
collection PubMed
description Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epidemic” obesity, with a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. At present, there is a growing interest on the role of visceral fat accumulation in the occurrence of MetS. In this review, the effects of adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of the MetS have been also emphasized. Accordingly, the “hypoadiponectinemia” has been proposed as the most interesting new hypothesis to explain the pathophysiology of MetS.
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spelling pubmed-31954292011-10-19 Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome Di Chiara, Tiziana Argano, Christiano Corrao, Salvatore Scaglione, Rosario Licata, Giuseppe J Nutr Metab Review Article Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epidemic” obesity, with a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. At present, there is a growing interest on the role of visceral fat accumulation in the occurrence of MetS. In this review, the effects of adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of the MetS have been also emphasized. Accordingly, the “hypoadiponectinemia” has been proposed as the most interesting new hypothesis to explain the pathophysiology of MetS. Hindawi Publishing Corporation 2012 2011-10-16 /pmc/articles/PMC3195429/ /pubmed/22013516 http://dx.doi.org/10.1155/2012/175245 Text en Copyright © 2012 Tiziana Di Chiara et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Di Chiara, Tiziana
Argano, Christiano
Corrao, Salvatore
Scaglione, Rosario
Licata, Giuseppe
Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title_full Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title_fullStr Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title_full_unstemmed Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title_short Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
title_sort hypoadiponectinemia: a link between visceral obesity and metabolic syndrome
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195429/
https://www.ncbi.nlm.nih.gov/pubmed/22013516
http://dx.doi.org/10.1155/2012/175245
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