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Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional ‘detour’ in the hemisected spinal cord
To encourage re-establishment of functional innervation of ipsilateral lumbar motoneurons by descending fibers after an intervening lateral thoracic (T10) hemisection (Hx), we treated adult rats with the following agents: (i) anti-Nogo-A antibodies to neutralize the growth-inhibitor Nogo-A; (ii) neu...
Autores principales: | Schnell, Lisa, Hunanyan, Arsen S, Bowers, William J, Horner, Philip J, Federoff, Howard J, Gullo, Miriam, Schwab, Martin E, Mendell, Lorne M, Arvanian, Victor L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195885/ https://www.ncbi.nlm.nih.gov/pubmed/21995852 http://dx.doi.org/10.1111/j.1460-9568.2011.07862.x |
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