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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies

Type 1 diabetes (T1D) is a chronic autoimmune disease and characterized by absolute insulin deficiency. β-cell replacement by islet cell transplantation has been established as a feasible treatment option for T1D. The two main obstacles after islet transplantation are alloreactive T-cell-mediated gr...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojie, Hao, Jianqiang, Metzger, Daniel L., Ao, Ziliang, Meloche, Mark, Verchere, C. Bruce, Chen, Lieping, Ou, Dawei, Mui, Alice, Warnock, Garth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196026/
https://www.ncbi.nlm.nih.gov/pubmed/22028949
http://dx.doi.org/10.1155/2011/418902