Extrasynaptic N-Methyl-d-aspartate (NMDA) Receptor Stimulation Induces Cytoplasmic Translocation of the CDKL5 Kinase and Its Proteasomal Degradation

Mutations in the X-linked gene cyclin-dependent kinase-like 5 (CDKL5) have been found in patients with epileptic encephalopathy characterized by early onset intractable epilepsy, including infantile spasms and other types of seizures, severe developmental delay, and often the development of Rett syn...

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Detalles Bibliográficos
Autores principales: Rusconi, Laura, Kilstrup-Nielsen, Charlotte, Landsberger, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196071/
https://www.ncbi.nlm.nih.gov/pubmed/21832092
http://dx.doi.org/10.1074/jbc.M111.235630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196071/
https://www.ncbi.nlm.nih.gov/pubmed/21832092
http://dx.doi.org/10.1074/jbc.M111.235630

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