Female Mucopolysaccharidosis IIIA Mice Exhibit Hyperactivity and a Reduced Sense of Danger in the Open Field Test

Reliable behavioural tests in animal models of neurodegenerative diseases allow us to study the natural history of disease and evaluate the efficacy of novel therapies. Mucopolysaccharidosis IIIA (MPS IIIA or Sanfilippo A), is a severe, neurodegenerative lysosomal storage disorder caused by a defici...

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Detalles Bibliográficos
Autores principales: Langford-Smith, Alex, Langford-Smith, Kia J., Jones, Simon A., Wynn, Robert F., Wraith, J. E., Wilkinson, Fiona L., Bigger, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196509/
https://www.ncbi.nlm.nih.gov/pubmed/22028789
http://dx.doi.org/10.1371/journal.pone.0025717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196509/
https://www.ncbi.nlm.nih.gov/pubmed/22028789
http://dx.doi.org/10.1371/journal.pone.0025717

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