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Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif
PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties. PEDF contains a secretion signal sequence, but although originally regarded as a secreted extracellular protein, endogenous PEDF is foun...
Autores principales: | Anguissola, Sergio, McCormack, William J., Morrin, Michelle A., Higgins, Wayne J., Fox, Denise M., Worrall, D. Margaret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196545/ https://www.ncbi.nlm.nih.gov/pubmed/22028839 http://dx.doi.org/10.1371/journal.pone.0026234 |
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