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Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

In the hypertrophied human heart, fatty acid metabolism is decreased and glucose utilisation is increased. We hypothesized that the sarcolemmal and mitochondrial proteins involved in these key metabolic pathways would mirror these changes, providing a mechanism to account for the modified metabolic...

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Detalles Bibliográficos
Autores principales: Heather, Lisa C., Howell, Neil J., Emmanuel, Yaso, Cole, Mark A., Frenneaux, Michael P., Pagano, Domenico, Clarke, Kieran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196577/
https://www.ncbi.nlm.nih.gov/pubmed/22028857
http://dx.doi.org/10.1371/journal.pone.0026326