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Synergy Between Intraepithelial Lymphocytes and Lamina Propria T Cells Drives Intestinal Inflammation During Infection
Oral infection of C57BL/6 mice with Toxoplasma gondii triggers severe necrosis in the ileum within 7–10 days of infection. Lesion development is mediated by Th-1 cytokines, CD4(+) T cells, and sub-epithelial bacterial translocation. As such, these features share similarity to Crohn’s disease. Recent...
Autores principales: | Egan, C. E., Maurer, K. J., Cohen, S. B., Mack, M., Simpson, K. W., Denkers, E. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196813/ https://www.ncbi.nlm.nih.gov/pubmed/21796113 http://dx.doi.org/10.1038/mi.2011.31 |
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