ATP Competitive Protein Kinase C Inhibitors Demonstrate Distinct State-Dependent Inhibition

We previously reported that some ATP competitive protein kinase C (PKC) inhibitors are either competitive or uncompetitive inhibitors with respect to substrate peptides. In this report, we demonstrate how the interactions between PKC and inhibitors change PKC activation kinetics. A substrate competi...

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Detalles Bibliográficos
Autores principales: Smith, Ida M., Hoshi, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197134/
https://www.ncbi.nlm.nih.gov/pubmed/22043317
http://dx.doi.org/10.1371/journal.pone.0026338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197134/
https://www.ncbi.nlm.nih.gov/pubmed/22043317
http://dx.doi.org/10.1371/journal.pone.0026338

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