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Lysine 92 Amino Acid Residue of USP46, a Gene Associated with ‘Behavioral Despair’ in Mice, Influences the Deubiquitinating Enzyme Activity
Deubiquitinating enzymes (DUBs) regulate diverse cellular functions by their activity of cleaving ubiquitin from specific protein substrates. Ubiquitin-Specific Protease 46 (USP46) has recently been identified as a quantitative trait gene responsible for immobility in the tail suspension test and fo...
Autores principales: | Zhang, Wei, Tian, Qing-Bao, Li, Qing-Kai, Wang, Jian-Min, Wang, Chao-Nan, Liu, Tian, Liu, Dian-Wu, Wang, Ming-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197135/ https://www.ncbi.nlm.nih.gov/pubmed/22043315 http://dx.doi.org/10.1371/journal.pone.0026297 |
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