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Up-Regulation of NDRG2 in Senescent Lens Epithelial Cells Contributes to Age-Related Cataract in Human

BACKGROUND: Human N-Myc downstream regulated gene2 (NDRG2), a novel gene has been cloned and shown to be related to a number of cellular processes, including proliferation, differentiation, stress, and apoptosis. NDRG2 has also been linked to age-related Alzheimer's disease. Since the role of t...

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Detalles Bibliográficos
Autores principales: Zhang, Zi-Feng, Zhang, Jian, Hui, Yan-Nian, Zheng, Min-Hua, Liu, Xin-Ping, Kador, Peter F., Wang, Yu-Sheng, Yao, Li-Bo, Zhou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197158/
https://www.ncbi.nlm.nih.gov/pubmed/22043305
http://dx.doi.org/10.1371/journal.pone.0026102