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Dissociation of Progressive Dopaminergic Neuronal Death and Behavioral Impairments by Bax Deletion in a Mouse Model of Parkinson's Diseases

Parkinson's disease (PD) is a common, late-onset movement disorder with selective degeneration of dopaminergic (DA) neurons in the substantia nigra (SN). Although the neurotoxin 6-hydroxydopamine (6-OHDA) has been used to induce progressive degeneration of DA neurons in various animal models of...

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Detalles Bibliográficos
Autores principales: Kim, Tae Woo, Moon, Younghye, Kim, Kyungjin, Lee, Jeong Eun, Koh, Hyun Chul, Rhyu, Im Joo, Kim, Hyun, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197195/
https://www.ncbi.nlm.nih.gov/pubmed/22043283
http://dx.doi.org/10.1371/journal.pone.0025346