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Dissociation of Progressive Dopaminergic Neuronal Death and Behavioral Impairments by Bax Deletion in a Mouse Model of Parkinson's Diseases
Parkinson's disease (PD) is a common, late-onset movement disorder with selective degeneration of dopaminergic (DA) neurons in the substantia nigra (SN). Although the neurotoxin 6-hydroxydopamine (6-OHDA) has been used to induce progressive degeneration of DA neurons in various animal models of...
Autores principales: | Kim, Tae Woo, Moon, Younghye, Kim, Kyungjin, Lee, Jeong Eun, Koh, Hyun Chul, Rhyu, Im Joo, Kim, Hyun, Sun, Woong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197195/ https://www.ncbi.nlm.nih.gov/pubmed/22043283 http://dx.doi.org/10.1371/journal.pone.0025346 |
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