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UPR in palmitate-treated pancreatic beta-cells is not affected by altering oxidation of the fatty acid

BACKGROUND: Elevated levels of lipids are detrimental for beta-cell function and mass. One of the mechanisms of how fatty acids induce apoptosis is development of the unfolded protein response (UPR). It is still far from understood how fatty acids activate the UPR, however. METHODS: We examined how...

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Detalles Bibliográficos
Autores principales:	Sargsyan, Ernest, Sol, E-ri Maria, Bergsten, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197479/ https://www.ncbi.nlm.nih.gov/pubmed/21978671 http://dx.doi.org/10.1186/1743-7075-8-70

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