Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice

BACKGROUND: The alveolar macrophage (AM) - first line of innate immune defence against pathogens and environmental irritants - constitutively expresses peroxisome-proliferator activated receptor γ (PPARγ). PPARγ ligand-induced activation keeps the AM quiescent, and thereby contributes to combat inva...

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Detalles Bibliográficos
Autores principales: Götz, Alexander A, Vidal-Puig, Antonio, Rödel, Heiko G, de Angelis, Martin Hrabé, Stoeger, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197489/
https://www.ncbi.nlm.nih.gov/pubmed/21933390
http://dx.doi.org/10.1186/1743-8977-8-28

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