3-Hydroxy Kynurenine Treatment Controls T. cruzi Replication and the Inflammatory Pathology Preventing the Clinical Symptoms of Chronic Chagas Disease

BACKGROUND: 3-Hydroxy Kynurenine (3-HK) administration during the acute phase of Trypanosoma. cruzi infection decreases the parasitemia of lethally infected mice and improves their survival. However, due to the fact that the treatment with 3-HK is unable to eradicate the parasite, together with the...

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Detalles Bibliográficos
Autores principales: Knubel, Carolina P., Martínez, Fernando F., Acosta Rodríguez, Eva V., Altamirano, Andrés, Rivarola, Héctor W., Diaz Luján, Cintia, Fretes, Ricardo E., Cervi, Laura, Motrán, Claudia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197528/
https://www.ncbi.nlm.nih.gov/pubmed/22028903
http://dx.doi.org/10.1371/journal.pone.0026550

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