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DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation
BACKGROUND: Cumulative evidence suggests that DNA secondary structures impact DNA replication, transcription and genomic rearrangements. One of the best studied examples is the recurrent constitutional t(11;22) in humans that is mediated by potentially cruciform-forming sequences at the breakpoints,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197554/ https://www.ncbi.nlm.nih.gov/pubmed/21899780 http://dx.doi.org/10.1186/1755-8166-4-18 |