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Subchronic Peripheral Neuregulin-1 Increases Ventral Hippocampal Neurogenesis and Induces Antidepressant-Like Effects
BACKGROUND: Adult hippocampal neurogenesis has been implicated in the mechanism of antidepressant action, and neurotrophic factors can mediate the neurogenic changes underlying these effects. The neurotrophic factor neuregulin-1 (NRG1) is involved in many aspects of brain development, from cell fate...
Autores principales: | Mahar, Ian, Tan, Stephanie, Davoli, Maria Antonietta, Dominguez-Lopez, Sergio, Qiang, Calvin, Rachalski, Adeline, Turecki, Gustavo, Mechawar, Naguib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197569/ https://www.ncbi.nlm.nih.gov/pubmed/22028923 http://dx.doi.org/10.1371/journal.pone.0026610 |
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