Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening

BACKGROUND: Duchenne muscular dystrophy (DMD) is a devastating muscle wasting disease caused by mutations in dystrophin, a muscle cytoskeletal protein. Utrophin is a homologue of dystrophin that can functionally compensate for its absence when expressed at increased levels in the myofibre, as shown...

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Detalles Bibliográficos
Autores principales: Moorwood, Catherine, Lozynska, Olga, Suri, Neha, Napper, Andrew D., Diamond, Scott L., Khurana, Tejvir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197614/
https://www.ncbi.nlm.nih.gov/pubmed/22028826
http://dx.doi.org/10.1371/journal.pone.0026169

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