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Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis

Sequencing of invasive strains of group A streptococci (GAS) has revealed a diverse array of single nucleotide polymorphisms in the gene encoding the control of virulence regulator (CovR) protein. However, there is limited information regarding the molecular mechanisms by which CovR single amino aci...

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Detalles Bibliográficos
Autores principales:	Horstmann, Nicola, Sahasrabhojane, Pranoti, Suber, Bryce, Kumaraswami, Muthiah, Olsen, Randall J., Flores, Anthony, Musser, James M., Brennan, Richard G., Shelburne, Samuel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197619/ https://www.ncbi.nlm.nih.gov/pubmed/22028655 http://dx.doi.org/10.1371/journal.ppat.1002311

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