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Near-Native Protein Loop Sampling Using Nonparametric Density Estimation Accommodating Sparcity
Unlike the core structural elements of a protein like regular secondary structure, template based modeling (TBM) has difficulty with loop regions due to their variability in sequence and structure as well as the sparse sampling from a limited number of homologous templates. We present a novel, knowl...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197639/ https://www.ncbi.nlm.nih.gov/pubmed/22028638 http://dx.doi.org/10.1371/journal.pcbi.1002234 |