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Microenvironmental Geometry Guides Platelet Adhesion and Spreading: A Quantitative Analysis at the Single Cell Level
To activate clot formation and maintain hemostasis, platelets adhere and spread onto sites of vascular injury. Although this process is well-characterized biochemically, how the physical and spatial cues in the microenvironment affect platelet adhesion and spreading remain unclear. In this study, we...
Autores principales: | Kita, Ashley, Sakurai, Yumiko, Myers, David R., Rounsevell, Ross, Huang, James N., Seok, Tae Joon, Yu, Kyoungsik, Wu, Ming C., Fletcher, Daniel A., Lam, Wilbur A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197646/ https://www.ncbi.nlm.nih.gov/pubmed/22028878 http://dx.doi.org/10.1371/journal.pone.0026437 |
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