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Microenvironmental Geometry Guides Platelet Adhesion and Spreading: A Quantitative Analysis at the Single Cell Level

To activate clot formation and maintain hemostasis, platelets adhere and spread onto sites of vascular injury. Although this process is well-characterized biochemically, how the physical and spatial cues in the microenvironment affect platelet adhesion and spreading remain unclear. In this study, we...

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Detalles Bibliográficos
Autores principales: Kita, Ashley, Sakurai, Yumiko, Myers, David R., Rounsevell, Ross, Huang, James N., Seok, Tae Joon, Yu, Kyoungsik, Wu, Ming C., Fletcher, Daniel A., Lam, Wilbur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197646/
https://www.ncbi.nlm.nih.gov/pubmed/22028878
http://dx.doi.org/10.1371/journal.pone.0026437

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