NHE Inhibition Does Not Improve Na(+) or Ca(2+) Overload During Reperfusion: Using Modeling to Illuminate the Mechanisms Underlying a Therapeutic Failure

Reperfusion injury results from pathologies of cardiac myocyte physiology that develop when previously ischemic myocardium experiences a restoration of normal perfusion. Events in the development of reperfusion injury begin with the restoration of a proton gradient upon reperfusion, which then allow...

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Detalles Bibliográficos
Autores principales: Roberts, Byron N., Christini, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197652/
https://www.ncbi.nlm.nih.gov/pubmed/22028644
http://dx.doi.org/10.1371/journal.pcbi.1002241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197652/
https://www.ncbi.nlm.nih.gov/pubmed/22028644
http://dx.doi.org/10.1371/journal.pcbi.1002241

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