Contribution of ARLTS1 Cys148Arg (T442C) Variant with Prostate Cancer Risk and ARLTS1 Function in Prostate Cancer Cells

ARLTS1 is a recently characterized tumor suppressor gene at 13q14.3, a region frequently deleted in both sporadic and hereditary prostate cancer (PCa). ARLTS1 variants, especially Cys148Arg (T442C), increase susceptibility to different cancers, including PCa. In this study the role of Cys148Arg subs...

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Detalles Bibliográficos
Autores principales: Siltanen, Sanna, Wahlfors, Tiina, Schindler, Martin, Saramäki, Outi R., Mpindi, John Patrick, Latonen, Leena, Vessella, Robert L., Tammela, Teuvo L. J., Kallioniemi, Olli, Visakorpi, Tapio, Schleutker, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197657/
https://www.ncbi.nlm.nih.gov/pubmed/22028916
http://dx.doi.org/10.1371/journal.pone.0026595

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