Identification of Widespread Ultra-Edited Human RNAs

Adenosine-to-inosine modification of RNA molecules (A-to-I RNA editing) is an important mechanism that increases transciptome diversity. It occurs when a genomically encoded adenosine (A) is converted to an inosine (I) by ADAR proteins. Sequencing reactions read inosine as guanosine (G); therefore,...

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Detalles Bibliográficos
Autores principales: Carmi, Shai, Borukhov, Itamar, Levanon, Erez Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197674/
https://www.ncbi.nlm.nih.gov/pubmed/22028664
http://dx.doi.org/10.1371/journal.pgen.1002317

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