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A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis
Using small molecule probes to understand gene function is an attractive approach that allows functional characterization of genes that are dispensable in standard laboratory conditions and provides insight into the mode of action of these compounds. Using chemogenomic assays we previously identifie...
Autores principales: | Lissina, Elena, Young, Brian, Urbanus, Malene L., Guan, Xue Li, Lowenson, Jonathan, Hoon, Shawn, Baryshnikova, Anastasia, Riezman, Isabelle, Michaut, Magali, Riezman, Howard, Cowen, Leah E., Wenk, Markus R., Clarke, Steven G., Giaever, Guri, Nislow, Corey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197675/ https://www.ncbi.nlm.nih.gov/pubmed/22028670 http://dx.doi.org/10.1371/journal.pgen.1002332 |
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