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Use of mobile phones and risk of brain tumours: update of Danish cohort study
Objective To investigate the risk of tumours in the central nervous system among Danish mobile phone subscribers. Design Nationwide cohort study. Setting Denmark. Participants All Danes aged ≥30 and born in Denmark after 1925, subdivided into subscribers and non-subscribers of mobile phones before 1...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197791/ https://www.ncbi.nlm.nih.gov/pubmed/22016439 http://dx.doi.org/10.1136/bmj.d6387 |
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author | Frei, Patrizia Poulsen, Aslak H Johansen, Christoffer Olsen, Jørgen H Steding-Jessen, Marianne Schüz, Joachim |
author_facet | Frei, Patrizia Poulsen, Aslak H Johansen, Christoffer Olsen, Jørgen H Steding-Jessen, Marianne Schüz, Joachim |
author_sort | Frei, Patrizia |
collection | PubMed |
description | Objective To investigate the risk of tumours in the central nervous system among Danish mobile phone subscribers. Design Nationwide cohort study. Setting Denmark. Participants All Danes aged ≥30 and born in Denmark after 1925, subdivided into subscribers and non-subscribers of mobile phones before 1995. Main outcome measures Risk of tumours of the central nervous system, identified from the complete Danish Cancer Register. Sex specific incidence rate ratios estimated with log linear Poisson regression models adjusted for age, calendar period, education, and disposable income. Results 358 403 subscription holders accrued 3.8 million person years. In the follow-up period 1990-2007, there were 10 729 cases of tumours of the central nervous system. The risk of such tumours was close to unity for both men and women. When restricted to individuals with the longest mobile phone use—that is, ≥13 years of subscription—the incidence rate ratio was 1.03 (95% confidence interval 0.83 to 1.27) in men and 0.91 (0.41 to 2.04) in women. Among those with subscriptions of ≥10 years, ratios were 1.04 (0.85 to 1.26) in men and 1.04 (0.56 to 1.95) in women for glioma and 0.90 (0.57 to 1.42) in men and 0.93 (0.46 to 1.87) in women for meningioma. There was no indication of dose-response relation either by years since first subscription for a mobile phone or by anatomical location of the tumour—that is, in regions of the brain closest to where the handset is usually held to the head. Conclusions In this update of a large nationwide cohort study of mobile phone use, there were no increased risks of tumours of the central nervous system, providing little evidence for a causal association. |
format | Online Article Text |
id | pubmed-3197791 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BMJ Publishing Group Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-31977912011-10-24 Use of mobile phones and risk of brain tumours: update of Danish cohort study Frei, Patrizia Poulsen, Aslak H Johansen, Christoffer Olsen, Jørgen H Steding-Jessen, Marianne Schüz, Joachim BMJ Research Objective To investigate the risk of tumours in the central nervous system among Danish mobile phone subscribers. Design Nationwide cohort study. Setting Denmark. Participants All Danes aged ≥30 and born in Denmark after 1925, subdivided into subscribers and non-subscribers of mobile phones before 1995. Main outcome measures Risk of tumours of the central nervous system, identified from the complete Danish Cancer Register. Sex specific incidence rate ratios estimated with log linear Poisson regression models adjusted for age, calendar period, education, and disposable income. Results 358 403 subscription holders accrued 3.8 million person years. In the follow-up period 1990-2007, there were 10 729 cases of tumours of the central nervous system. The risk of such tumours was close to unity for both men and women. When restricted to individuals with the longest mobile phone use—that is, ≥13 years of subscription—the incidence rate ratio was 1.03 (95% confidence interval 0.83 to 1.27) in men and 0.91 (0.41 to 2.04) in women. Among those with subscriptions of ≥10 years, ratios were 1.04 (0.85 to 1.26) in men and 1.04 (0.56 to 1.95) in women for glioma and 0.90 (0.57 to 1.42) in men and 0.93 (0.46 to 1.87) in women for meningioma. There was no indication of dose-response relation either by years since first subscription for a mobile phone or by anatomical location of the tumour—that is, in regions of the brain closest to where the handset is usually held to the head. Conclusions In this update of a large nationwide cohort study of mobile phone use, there were no increased risks of tumours of the central nervous system, providing little evidence for a causal association. BMJ Publishing Group Ltd. 2011-10-20 /pmc/articles/PMC3197791/ /pubmed/22016439 http://dx.doi.org/10.1136/bmj.d6387 Text en © Frei et al 2011 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode. |
spellingShingle | Research Frei, Patrizia Poulsen, Aslak H Johansen, Christoffer Olsen, Jørgen H Steding-Jessen, Marianne Schüz, Joachim Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title | Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title_full | Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title_fullStr | Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title_full_unstemmed | Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title_short | Use of mobile phones and risk of brain tumours: update of Danish cohort study |
title_sort | use of mobile phones and risk of brain tumours: update of danish cohort study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197791/ https://www.ncbi.nlm.nih.gov/pubmed/22016439 http://dx.doi.org/10.1136/bmj.d6387 |
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