Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model

Recent studies have shown that immunotherapy clears amyloid beta (Aβ) plaques and reduces Aβ levels in mouse models of Alzheimer’s disease (AD), as well as in AD patients. Tangle pathology is also relevant for the neurodegeneration in AD, and our studies have shown that active immunization with an A...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Pavan K., Deng, Yan, Sigurdsson, Einar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198029/
https://www.ncbi.nlm.nih.gov/pubmed/22025915
http://dx.doi.org/10.3389/fpsyt.2011.00059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198029/
https://www.ncbi.nlm.nih.gov/pubmed/22025915
http://dx.doi.org/10.3389/fpsyt.2011.00059

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