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Elevated NF-κB Activation Is Conserved in Human Myocytes Cultured From Obese Type 2 Diabetic Patients and Attenuated by AMP-Activated Protein Kinase

OBJECTIVE: To examine whether the inflammatory phenotype found in obese and diabetic individuals is preserved in isolated, cultured myocytes and to assess the effectiveness of pharmacological AMP-activated protein kinase (AMPK) activation upon the attenuation of inflammation in these myocytes. RESEA...

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Detalles Bibliográficos
Autores principales: Green, Charlotte J., Pedersen, Maria, Pedersen, Bente K., Scheele, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198079/
https://www.ncbi.nlm.nih.gov/pubmed/21911750
http://dx.doi.org/10.2337/db11-0263