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Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats

OBJECTIVE: Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabolic processes. We investigate the site of resveratrol action on glucose metabolism and the contribution of SIRT1 to these effects. Because the arcuate nucleus in the mediobasal hypothalamus (MBH) pla...

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Detalles Bibliográficos
Autores principales:	Knight, Colette M., Gutierrez-Juarez, Roger, Lam, Tony K.T., Arrieta-Cruz, Isabel, Huang, Loli, Schwartz, Gary, Barzilai, Nir, Rossetti, Luciano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198094/ https://www.ncbi.nlm.nih.gov/pubmed/21896928 http://dx.doi.org/10.2337/db10-0987

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