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The tRNA(Met) 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree

Mutations in mitochondrial DNA (mtDNA) have been associated with hypertension in several pedigrees with maternal inheritance. However, the pathophysiology of maternally inherited hypertension remains poorly understood. We reported here clinical, genetic evaluations and molecular analysis of mtDNA in...

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Detalles Bibliográficos
Autores principales:	Lu, Zhongqiu, Chen, Hong, Meng, Yanzi, Wang, Yan, Xue, Ling, Zhi, Shaoce, Qiu, Qiaomeng, Yang, Li, Mo, Jun Qin, Guan, Min-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198143/ https://www.ncbi.nlm.nih.gov/pubmed/21694735 http://dx.doi.org/10.1038/ejhg.2011.111

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