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The effects of magnesium sulfate infiltration on perioperative opioid consumption and opioid-induced hyperalgesia in patients undergoing robot-assisted laparoscopic prostatectomy with remifentanil-based anesthesia

BACKGROUND: Opioids not only exert an antinociceptive effect, but also modulate central N-methyl-D-aspartate (NMDA) receptors, resulting in hyperalgesia and acute opioid tolerance. This study was aimed to investigate the effect of the NMDA receptor antagonist, magnesium in preventing remifentanil-in...

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Detalles Bibliográficos
Autores principales:	Lee, Cheol, Song, Yoon-Kang, Jeong, Hyun-Myun, Park, Seong-Nam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Anesthesiologists 2011
Materias:	Clinical Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198187/ https://www.ncbi.nlm.nih.gov/pubmed/22025948 http://dx.doi.org/10.4097/kjae.2011.61.3.244

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