Comprehensive Evaluation of One-Carbon Metabolism Pathway Gene Variants and Renal Cell Cancer Risk

INTRODUCTION: Folate and one-carbon metabolism are linked to cancer risk through their integral role in DNA synthesis and methylation. Variation in one-carbon metabolism genes, particularly MTHFR, has been associated with risk of a number of cancers in epidemiologic studies, but little is known rega...

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Detalles Bibliográficos
Autores principales: Gibson, Todd M., Brennan, Paul, Han, Summer, Karami, Sara, Zaridze, David, Janout, Vladimir, Kollarova, Helen, Bencko, Vladimir, Navratilova, Marie, Szeszenia-Dabrowska, Neonila, Mates, Dana, Slamova, Alena, Pfeiffer, Ruth M., Stolzenberg-Solomon, Rachael Z., Mayne, Susan T., Yeager, Meredith, Chanock, Stephen, Rothman, Nat, Chow, Wong-Ho, Rosenberg, Philip S., Boffetta, Paolo, Moore, Lee E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198392/
https://www.ncbi.nlm.nih.gov/pubmed/22039442
http://dx.doi.org/10.1371/journal.pone.0026165

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