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Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase Inhibitors
Radiotherapy (RT) plays a key role in cancer treatment. Although the benefit of ionizing radiation (IR) is well established, some findings raise the possibility that irradiation of the primary tumor not only triggers a killing response but also increases the metastatic potential of surviving tumor c...
Autores principales: | Hamalukic, Melanie, Huelsenbeck, Johannes, Schad, Arno, Wirtz, Stefan, Kaina, Bernd, Fritz, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198428/ https://www.ncbi.nlm.nih.gov/pubmed/22039482 http://dx.doi.org/10.1371/journal.pone.0026413 |
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