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Targeted Decorin Gene Therapy Delivered with Adeno-Associated Virus Effectively Retards Corneal Neovascularization In Vivo

Decorin, small leucine-rich proteoglycan, has been shown to modulate angiogenesis in nonocular tissues. This study tested a hypothesis that tissue-selective targeted decorin gene therapy delivered to the rabbit stroma with adeno-associated virus serotype 5 (AAV5) impedes corneal neovascularization (...

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Detalles Bibliográficos
Autores principales:	Mohan, Rajiv R., Tovey, Jonathan C. K., Sharma, Ajay, Schultz, Gregory S., Cowden, John W., Tandon, Ashish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198476/ https://www.ncbi.nlm.nih.gov/pubmed/22039486 http://dx.doi.org/10.1371/journal.pone.0026432

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