Cargando…

Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses

Sensing of infectious danger by toll-like receptors (TLRs) on macrophages causes not only a reprogramming of the transcriptome but also changes in the cytoskeleton important for cell spreading and motility. Since manual determination of cell contact areas from fluorescence micrographs is very time-c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wenzel, Jens, Held, Christian, Palmisano, Ralf, Teufel, Stefan, David, Jean-Pierre, Wittenberg, Thomas, Lang, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198511/ https://www.ncbi.nlm.nih.gov/pubmed/22028692 http://dx.doi.org/10.3389/fphys.2011.00071

Ejemplares similares

Anti-inflammatory and Regulatory Effects of Huanglian Jiedu Decoction on Lipid Homeostasis and the TLR4/MyD88 Signaling Pathway in LPS-Induced Zebrafish
por: Zhou, Junyi, et al.
Publicado: (2019)

MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin
por: Samba-Mondonga, Macha, et al.
Publicado: (2018)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas
por: Küppers, Ralf
Publicado: (2015)

MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice
por: Layoun, Antonio, et al.
Publicado: (2018)

Highlighting of the interactions of MYD88 and NFKB1 SNPs in rats resistant to decompression sickness: toward an autoimmune response
por: Vallée, Nicolas, et al.
Publicado: (2023)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway
por: Hu, Dan, et al.
Publicado: (2022)

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo
por: Dutta, Debashis, et al.
Publicado: (2021)

Peripheral Immune Activation in Mice Elicits Unfolded Protein Responses Independent on MyD88 Pathway in the Liver but not the Hypothalamus and Hippocampus
por: Yamawaki, Yosuke, et al.
Publicado: (2022)

Wheat oligopeptides enhance the intestinal mucosal barrier and alleviate inflammation via the TLR4/Myd88/MAPK signaling pathway in aged mice
por: Xian, Yang, et al.
Publicado: (2022)

TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis
por: Abdelsalam, Hadeer M., et al.
Publicado: (2022)

Aberrant Expression of TLR2, TLR7, TLR9, Splicing Variants of TLR4 and MYD88 in Chronic Lymphocytic Leukemia Patients
por: Skorka, Katarzyna, et al.
Publicado: (2021)

TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection
por: Kuriakose, Shiby, et al.
Publicado: (2019)

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
por: Li, Baojing, et al.
Publicado: (2022)

Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
por: Kim, Ki Hyung, et al.
Publicado: (2012)

TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells
por: Wu, Kunlin, et al.
Publicado: (2018)

TLR/MyD88-mediated Innate Immunity in Intestinal Graft-versus-Host Disease
por: Lee, Young-Kwan, et al.
Publicado: (2017)

The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
por: Pereira, Milton, et al.
Publicado: (2022)

Roles of TLR/MyD88/MAPK/NF-κB Signaling Pathways in the Regulation of Phagocytosis and Proinflammatory Cytokine Expression in Response to E. faecalis Infection
por: Zou, Jun, et al.
Publicado: (2015)

MyD88 Is Required for Efficient Control of Coxiella burnetii Infection and Dissemination
por: Kohl, Lisa, et al.
Publicado: (2019)

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis
por: Castoldi, Angela, et al.
Publicado: (2012)

TLR2 and TLR4 Mediate Differential Responses to Limb Ischemia through MyD88-Dependent and Independent Pathways
por: Sachdev, Ulka, et al.
Publicado: (2012)

TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury
por: Hussain, Salik, et al.
Publicado: (2020)

Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent
por: Udayan, Sreeram, et al.
Publicado: (2021)

Mycobacterium tuberculosis Subverts the TLR-2 - MyD88 Pathway to Facilitate Its Translocation into the Cytosol
por: Rahman, Md. Aejazur, et al.
Publicado: (2014)

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways
por: Pang, Zheng, et al.
Publicado: (2018)

Lack of Associations between TLR9 and MYD88 Gene Polymorphisms and Risk of Chronic Lymphocytic Leukemia
por: Ali, Yasser B.M, et al.
Publicado: (2017)

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
por: Rangasamy, Suresh B., et al.
Publicado: (2018)

Enhanced Calvarial Bone Healing in CD11c-TLR4(−/−) and MyD88(−/−) Mice
por: Wang, Dan, et al.
Publicado: (2017)

The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer
por: Bates, Mark, et al.
Publicado: (2020)

Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils
por: Müller, Beate J., et al.
Publicado: (2021)

Frutescone O from Baeckea frutescens Blocked TLR4-Mediated Myd88/NF-κB and MAPK Signaling Pathways in LPS Induced RAW264.7 Macrophages
por: Lin, Xiaobing, et al.
Publicado: (2021)

SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas
por: Munshi, Manit, et al.
Publicado: (2020)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

TLR2, TLR4 and the MyD88 Signaling Are Crucial For the In Vivo Generation and the Longevity of Long-Lived Antibody-Secreting Cells
por: Komegae, Evilin Naname, et al.
Publicado: (2013)

TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD
por: Thorburn, Alison N., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_svbbj49n3g14k7d2kl2ib0c0j9