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Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor
Vascular endothelial growth factor (VEGF) blockade is an effective therapy for human cancer, yet virtually all neoplasms resume primary tumor growth or metastasize during therapy. Mechanisms of progression have been proposed to include genes that control vascular remodeling and are elicited by hypop...
Autores principales: | Fisher, Jason C, Gander, Jeffrey W, Haley, Mary Jo, Hernandez, Sonia L, Huang, Jianzhong, Chang, Yan-Jung, Johung, Tessa B, Guarnieri, Paolo, O'Toole, Kathleen, Yamashiro, Darrell J, Kandel, Jessica J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198683/ https://www.ncbi.nlm.nih.gov/pubmed/21978392 http://dx.doi.org/10.1186/2045-824X-3-22 |
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