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Mitochondrial DNA alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy

BACKGROUND: Mitochondrial DNA (mtDNA) alterations, including mtDNA copy number and mtDNA 4977 bp common deletion (CD), are key indicators of irradiation-induced damage. The relationship between total body irradiation (TBI) treatment and mtDNA alterations in vivo, however, has not been postulated yet...

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Detalles Bibliográficos
Autores principales:	Wen, Quan, Hu, Yide, Ji, Fuyun, Qian, Guisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198693/ https://www.ncbi.nlm.nih.gov/pubmed/21978541 http://dx.doi.org/10.1186/1748-717X-6-133

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