Cargando…

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

BACKGROUND: Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarrhea, gastrointestinal bleeding and high mortality can be observed. Because surv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Noth, Rainer, Lange-Grumfeld, Julia, Stüber, Eckhard, Kruse, Marie-Luise, Ellrichmann, Mark, Häsler, Robert, Hampe, Jochen, Bewig, Burkhard, Rosenstiel, Philip, Schreiber, Stefan, Arlt, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198696/ https://www.ncbi.nlm.nih.gov/pubmed/21977944 http://dx.doi.org/10.1186/1471-230X-11-109

Ejemplares similares

A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier
por: Wong, Vivian, et al.
Publicado: (1997)

Possible Involvement of Phosphorylation of Occludin in Tight Junction Formation
por: Sakakibara, Akira, et al.
Publicado: (1997)

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
Publicado: (1994)

Oncogenic Raf-1 Disrupts Epithelial Tight Junctions via Downregulation of Occludin
por: Li, Danxi, et al.
Publicado: (2000)

Early Porcine Sapovirus Infection Disrupts Tight Junctions and Uses Occludin as a Coreceptor
por: Alfajaro, Mia Madel, et al.
Publicado: (2019)

Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability
por: Huang, Bill X., et al.
Publicado: (2023)

Occludin: a novel integral membrane protein localizing at tight junctions
Publicado: (1993)

Modulation of Tight Junction Structure and Function by Kinases and Phosphatases Targeting Occludin
por: Dörfel, Max Johannes, et al.
Publicado: (2012)

Newly synthesized claudins but not occludin are added to the basal side of the tight junction
por: Van Itallie, Christina M., et al.
Publicado: (2019)

Connexin-Occludin Chimeras Containing the Zo-Binding Domain of Occludin Localize at Mdck Tight Junctions and Nrk Cell Contacts
por: Mitic, Laura L., et al.
Publicado: (1999)

The Reversible Increase in Tight Junction Permeability Induced by Capsaicin Is Mediated via Cofilin-Actin Cytoskeletal Dynamics and Decreased Level of Occludin
por: Shiobara, Tomoko, et al.
Publicado: (2013)

Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function
por: Raleigh, David R., et al.
Publicado: (2011)

Protein Kinase Cβ Phosphorylates Occludin Regulating Tight Junction Trafficking in Vascular Endothelial Growth Factor–Induced Permeability In Vivo
por: Murakami, Tomoaki, et al.
Publicado: (2012)

COOH Terminus of Occludin Is Required for Tight Junction Barrier Function in Early Xenopus Embryos
por: Chen, Yan-hua, et al.
Publicado: (1997)

Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro
por: Lehmann, Andrea D, et al.
Publicado: (2009)

Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro
por: McCabe, Mark J, et al.
Publicado: (2016)

Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex
por: Bendriem, Raphael M, et al.
Publicado: (2019)

Expressions of Tight Junction Proteins Occludin and Claudin-1 Are under the Circadian Control in the Mouse Large Intestine: Implications in Intestinal Permeability and Susceptibility to Colitis
por: Oh-oka, Kyoko, et al.
Publicado: (2014)

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
por: Marchiando, Amanda M., et al.
Publicado: (2010)

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
por: Steed, Emily, et al.
Publicado: (2009)

β-Conglycinin Reduces the Tight Junction Occludin and ZO-1 Expression in IPEC-J2
por: Zhao, Yuan, et al.
Publicado: (2014)

CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity
por: Dörfel, Max J, et al.
Publicado: (2013)

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux
por: Buschmann, Mary M., et al.
Publicado: (2013)

Upregulation of the tight junction protein occludin: effects on ventilation-induced lung injury and mechanisms of action
por: Liu, Mengjie, et al.
Publicado: (2014)

A 22-amino-acid peptide regulates tight junctions through occludin and cell apoptosis
por: Zhu, Maoying, et al.
Publicado: (2020)

The Effect of Exposure to Bisphenol A on Spermatozoon and the Expression of Tight Junction Protein Occludin in Male Mice
por: Cao, Tingshuai, et al.
Publicado: (2020)

Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function
por: Saito, Akira C., et al.
Publicado: (2021)

DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction
por: Chou, Hsiao-Chin, et al.
Publicado: (2022)

Tight Junction Claudins and Occludin Are Differentially Regulated and Expressed in Genomically Defined Subsets of Colon Cancer
por: Voutsadakis, Ioannis A.
Publicado: (2023)

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions
por: Saitou, Mitinori, et al.
Publicado: (1998)

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin
por: Furuse, Mikio, et al.
Publicado: (1998)

Proteomic and cellular localisation studies suggest non‐tight junction cytoplasmic and nuclear roles for occludin in astrocytes
por: Morgan, Sarah V., et al.
Publicado: (2018)

A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts
por: Furuse, Mikio, et al.
Publicado: (1998)

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions
por: Raleigh, David R., et al.
Publicado: (2010)

Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ‐mediated phosphorylation of occludin
por: Kalsi, Kameljit K., et al.
Publicado: (2018)

Fusion expression of Occludin extracellular loops and an α-helical bundle: A new research model for tight junction
por: Chi, Xiaojing, et al.
Publicado: (2017)

miR-122-5p regulates the tight junction of the blood-testis barrier of mice via occludin: miR-122-5p can regulate the tight junction
por: Liu, Limin, et al.
Publicado: (2021)

ZO-3, a Novel Member of the MAGUK Protein Family Found at the Tight Junction, Interacts with ZO-1 and Occludin
por: Haskins, Julie, et al.
Publicado: (1998)

The tight junction protein occludin modulates blood–brain barrier integrity and neurological function after ischemic stroke in mice
por: Sugiyama, Shintaro, et al.
Publicado: (2023)

The EhCPADH112 Complex of Entamoeba histolytica Interacts with Tight Junction Proteins Occludin and Claudin-1 to Produce Epithelial Damage
por: Betanzos, Abigail, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_veq5ea3e60ttlb1s5num2sovuh