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Monocyte Chemoattractant Protein-1-Deficiency Impairs the Expression of IL-6, IL-1β and G-CSF after Transient Focal Ischemia in Mice
Monocyte chemoattractant protein-1 (MCP-1), a chemokine secreted by neurons and astrocytes following stroke is known to aggravate ischemia-related damage. Previous studies revealed that MCP-1-deficient mice develop smaller infarcts and have an improved neurological outcome, whereas mice overexpressi...
Autores principales: | Strecker, Jan-Kolja, Minnerup, Jens, Gess, Burkhard, Ringelstein, E. Bernd, Schäbitz, Wolf-Rüdiger, Schilling, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198727/ https://www.ncbi.nlm.nih.gov/pubmed/22031820 http://dx.doi.org/10.1371/journal.pone.0025863 |
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