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Induction of a Protective Response in Mice by the Dengue Virus NS3 Protein Using DNA Vaccines
The dengue non-structural 3 (NS3) is a multifunctional protein, containing a serino-protease domain, located at the N-terminal portion, and helicase, NTPase and RTPase domains present in the C-terminal region. This protein is considered the main target for CD4+ and CD8+ T cell responses during dengu...
Autores principales: | Costa, Simone M., Yorio, Anna Paula, Gonçalves, Antônio J. S., Vidale, Mariana M., Costa, Emmerson C. B., Mohana-Borges, Ronaldo, Motta, Marcia A., Freire, Marcos S., Alves, Ada M. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198735/ https://www.ncbi.nlm.nih.gov/pubmed/22031819 http://dx.doi.org/10.1371/journal.pone.0025685 |
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