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Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children

Objectives. To investigate whether lifestyle-only intervention in obese children who maintain or lose a modest amount of weight redistributes parameters of body composition and reverses metabolic abnormalities. Study Design. Clinical, anthropometric, and metabolic parameters were assessed in 111 ove...

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Autores principales: Marcano, Henry, Fernández, Maricelia, Paoli, Mariela, Santomauro, Mercedes, Camacho, Nolis, Cichetti, Rosanna, Molina, Zarela, Valeri, Lenin, Lanes, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198742/
https://www.ncbi.nlm.nih.gov/pubmed/21603203
http://dx.doi.org/10.1155/2011/241703
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author Marcano, Henry
Fernández, Maricelia
Paoli, Mariela
Santomauro, Mercedes
Camacho, Nolis
Cichetti, Rosanna
Molina, Zarela
Valeri, Lenin
Lanes, Roberto
author_facet Marcano, Henry
Fernández, Maricelia
Paoli, Mariela
Santomauro, Mercedes
Camacho, Nolis
Cichetti, Rosanna
Molina, Zarela
Valeri, Lenin
Lanes, Roberto
author_sort Marcano, Henry
collection PubMed
description Objectives. To investigate whether lifestyle-only intervention in obese children who maintain or lose a modest amount of weight redistributes parameters of body composition and reverses metabolic abnormalities. Study Design. Clinical, anthropometric, and metabolic parameters were assessed in 111 overweight or obese children (CA of 11.3 ± 2.8 years; 63 females and 48 males), during 8 months of lifestyle intervention. Patients maintained or lost weight (1–5%) (group A; n: 72) or gained weight (group B). Results. Group A patients presented with a decrease in systolic blood pressure (SBP) and diastolic blood pressure (DBP) ([Image: see text] and [Image: see text], resp.), BMI ([Image: see text]), z-score BMI ([Image: see text]), waist circumference ([Image: see text]), fat mass ([Image: see text]), LDL-C ([Image: see text]), Tg/HDL-C ratio ([Image: see text]), fasting and postprandial insulin ([Image: see text]), and HOMA ([Image: see text]), while HDL-C ([Image: see text]) and QUICKI increased ([Image: see text]). Conversely, group B patients had an increase in BMI ([Image: see text]), waist circumference ([Image: see text]), SBP ([Image: see text]), and in QUICKI ([Image: see text]), while fat mass ([Image: see text]), fasting insulin ([Image: see text]), and HOMA ([Image: see text]) decreased. Lean mass, DBP, lipid concentrations, fasting and postprandial glucose, postprandial insulin, and ultrasensitive C-reactive protein (CRP) remained stable. Conclusions. Obese children who maintain or lose a modest amount of weight following lifestyle-only intervention tend to redistribute their body fat, decrease blood pressure and lipid levels, and to improve parameters of insulin sensitivity.
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spelling pubmed-31987422011-10-23 Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children Marcano, Henry Fernández, Maricelia Paoli, Mariela Santomauro, Mercedes Camacho, Nolis Cichetti, Rosanna Molina, Zarela Valeri, Lenin Lanes, Roberto Int J Pediatr Endocrinol Clinical Study Objectives. To investigate whether lifestyle-only intervention in obese children who maintain or lose a modest amount of weight redistributes parameters of body composition and reverses metabolic abnormalities. Study Design. Clinical, anthropometric, and metabolic parameters were assessed in 111 overweight or obese children (CA of 11.3 ± 2.8 years; 63 females and 48 males), during 8 months of lifestyle intervention. Patients maintained or lost weight (1–5%) (group A; n: 72) or gained weight (group B). Results. Group A patients presented with a decrease in systolic blood pressure (SBP) and diastolic blood pressure (DBP) ([Image: see text] and [Image: see text], resp.), BMI ([Image: see text]), z-score BMI ([Image: see text]), waist circumference ([Image: see text]), fat mass ([Image: see text]), LDL-C ([Image: see text]), Tg/HDL-C ratio ([Image: see text]), fasting and postprandial insulin ([Image: see text]), and HOMA ([Image: see text]), while HDL-C ([Image: see text]) and QUICKI increased ([Image: see text]). Conversely, group B patients had an increase in BMI ([Image: see text]), waist circumference ([Image: see text]), SBP ([Image: see text]), and in QUICKI ([Image: see text]), while fat mass ([Image: see text]), fasting insulin ([Image: see text]), and HOMA ([Image: see text]) decreased. Lean mass, DBP, lipid concentrations, fasting and postprandial glucose, postprandial insulin, and ultrasensitive C-reactive protein (CRP) remained stable. Conclusions. Obese children who maintain or lose a modest amount of weight following lifestyle-only intervention tend to redistribute their body fat, decrease blood pressure and lipid levels, and to improve parameters of insulin sensitivity. BioMed Central 2011 2011-03-14 /pmc/articles/PMC3198742/ /pubmed/21603203 http://dx.doi.org/10.1155/2011/241703 Text en Copyright © 2011 Copyright © 2011 Henry Marcano et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Marcano, Henry
Fernández, Maricelia
Paoli, Mariela
Santomauro, Mercedes
Camacho, Nolis
Cichetti, Rosanna
Molina, Zarela
Valeri, Lenin
Lanes, Roberto
Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title_full Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title_fullStr Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title_full_unstemmed Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title_short Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children
title_sort limited weight loss or simply no weight gain following lifestyle-only intervention tends to redistribute body fat, to decrease lipid concentrations, and to improve parameters of insulin sensitivity in obese children
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198742/
https://www.ncbi.nlm.nih.gov/pubmed/21603203
http://dx.doi.org/10.1155/2011/241703
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