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Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells

BACKGROUND: Withaferin A (WA), a naturally occurring withanolide, induces apoptosis in both estrogen-responsive MCF-7 and estrogen-independent MDA-MB-231 breast cancer cell lines with higher sensitivity in MCF-7 cells, but the underlying mechanisms are not well defined. The purpose of this study was...

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Detalles Bibliográficos
Autores principales:	Zhang, Xuan, Mukerji, Ridhwi, Samadi, Abbas K, Cohen, Mark S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198756/ https://www.ncbi.nlm.nih.gov/pubmed/21978374 http://dx.doi.org/10.1186/1472-6882-11-84

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