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Modulation of Cardiac Ryanodine Receptor Channels by Alkaline Earth Cations

Cardiac ryanodine receptor (RyR2) function is modulated by Ca(2+) and Mg(2+). To better characterize Ca(2+) and Mg(2+) binding sites involved in RyR2 regulation, the effects of cytosolic and luminal earth alkaline divalent cations (M(2+): Mg(2+), Ca(2+), Sr(2+), Ba(2+)) were studied on RyR2 from pig...

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Detalles Bibliográficos
Autores principales: Diaz-Sylvester, Paula L., Porta, Maura, Copello, Julio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198824/
https://www.ncbi.nlm.nih.gov/pubmed/22039534
http://dx.doi.org/10.1371/journal.pone.0026693