Targeted gene correction of α(1)-antitrypsin deficiency in induced pluripotent stem cells

Human induced pluripotent stem cells (hIPSCs) represent a unique opportunity for regenerative medicine since they offer the prospect of generating unlimited quantities of cells for autologous transplantation as a novel treatment for a broad range of disorders(1,2,3,4). However, the use of hIPSCs in...

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Detalles Bibliográficos
Autores principales: Yusa, Kosuke, Rashid, S. Tamir, Strick-Marchand, Helene, Varela, Ignacio, Liu, Pei-Qi, Paschon, David E., Miranda, Elena, Ordóñez, Adriana, Hannan, Nick, Rouhani, Foad Jafari, Darche, Sylvie, Alexander, Graeme, Marciniak, Stefan J., Fusaki, Noemi, Hasegawa, Mamoru, Holmes, Michael C., Di Santo, James P., Lomas, David A., Bradley, Allan, Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198846/
https://www.ncbi.nlm.nih.gov/pubmed/21993621
http://dx.doi.org/10.1038/nature10424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198846/
https://www.ncbi.nlm.nih.gov/pubmed/21993621
http://dx.doi.org/10.1038/nature10424

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