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Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells

BACKGROUND: Old age is associated with increased levels of circulating pro-inflammatory cytokines, a phenomenon termed inflamm-aging. Elevated levels of pro-inflammatory cytokines have been associated with several age-associated diseases and with a shortened lifespan. Indoleamine 2,3-dioxygenase (ID...

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Detalles Bibliográficos
Autores principales:	Marttila, Saara, Jylhävä, Juulia, Eklund, Carita, Hervonen, Antti, Jylhä, Marja, Hurme, Mikko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198939/ https://www.ncbi.nlm.nih.gov/pubmed/21989355 http://dx.doi.org/10.1186/1742-4933-8-9

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