Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells

INTRODUCTION: Bcl-xL, an important member of anti-apoptotic Bcl-2 family, plays critical roles in tumor progression and development. Previously, we have reported that overexpression of Bcl-xL was correlated with prognosis of colorectal cancer (CRC) patients. The aim of this study was to investigate...

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Detalles Bibliográficos
Autores principales: Yang, Jinsong, Sun, Ming, Zhang, Aiping, Lv, Chengyu, De, Wei, Wang, Zhaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198948/
https://www.ncbi.nlm.nih.gov/pubmed/21970601
http://dx.doi.org/10.1186/1477-7819-9-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198948/
https://www.ncbi.nlm.nih.gov/pubmed/21970601
http://dx.doi.org/10.1186/1477-7819-9-117

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