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Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells
INTRODUCTION: Bcl-xL, an important member of anti-apoptotic Bcl-2 family, plays critical roles in tumor progression and development. Previously, we have reported that overexpression of Bcl-xL was correlated with prognosis of colorectal cancer (CRC) patients. The aim of this study was to investigate...
Autores principales: | Yang, Jinsong, Sun, Ming, Zhang, Aiping, Lv, Chengyu, De, Wei, Wang, Zhaoxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198948/ https://www.ncbi.nlm.nih.gov/pubmed/21970601 http://dx.doi.org/10.1186/1477-7819-9-117 |
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