Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

BACKGROUND: Patient selection for phase I trials (PIT) in oncology is challenging. A typical inclusion criterion for PIT is 'life expectancy > 3 months', however the 90 day mortality (90DM) and overall survival (OS) of patients with advanced solid malignancies are difficult to predict....

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Detalles Bibliográficos
Autores principales: Chau, Nicole G, Florescu, Ana, Chan, Kelvin K, Wang, Lisa, Chen, Eric X, Bedard, Philippe, Oza, Amit M, Siu, Lillian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199018/
https://www.ncbi.nlm.nih.gov/pubmed/21975023
http://dx.doi.org/10.1186/1471-2407-11-426

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